Medical Researches
Moderately Effective
Based on 16 Researches
We aimed to understand how curcumin, a compound found in turmeric, impacts knee pain in individuals suffering from osteoarthritis (OA). Using various databases, we gathered and analyzed data from multiple meta-analyses that included randomized controlled trials focused on curcumin's effects on OA symptoms up to September 2023.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
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Topical curcumin gel effectivenessRevolutionizing Knee Osteoarthritis Treatment: Innovative Self-Nano-Emulsifying Polyethylene Glycol Organogel of Curcumin for Effective Topical Delivery.
Relevant but not directly turmeric
We conducted a study to explore the effectiveness of a unique topical gel infused with curcumin, a key ingredient in turmeric, for treating knee osteoarthritis. This innovative gel utilizes a self-nano-emulsifying organogel system, which allows for better delivery of curcumin, a compound known for its challenging solubility and stability issues.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
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Turmeric improves knee osteoarthritisA standardized nutraceutical supplement contributes to pain relief, improves quality of life and regulates inflammation in knee osteoarthritis patients; A randomized clinical trial.
Moderate relevance to knee pain
Our study focused on the impact of a specific combination of polyphenolic supplements, including turmeric, on knee pain for individuals with osteoarthritis. We conducted a randomized controlled trial with 60 participants, half of whom received the polyphenolic supplement featuring turmeric, rosemary extract, and resveratrol, while the other half received a placebo.
Over the course of 12 weeks, those taking the polyphenol supplement reported significantly reduced pain levels and improved physical functionality. The data was collected using validated questionnaires, demonstrating clearer benefits in this group compared to those on the placebo.
Notably, we observed that the polyphenol supplement also helped reduce systemic inflammation, which could be a key factor in easing knee pain. This suggests that turmeric, as part of the supplement, may play a beneficial role in managing not just pain, but also the overall quality of life for those suffering from knee osteoarthritis.
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We studied the effects of curcumin, a compound in turmeric, alongside swimming to see how this combination could help alleviate knee pain caused by osteoarthritis (OA). In our research with rats, we set up five groups, with some getting the treatment and others serving as a control.
After injecting a substance that induces OA, we began a daily swimming regimen for certain groups and provided them with oral curcumin over four weeks. This combination proved to be the most effective in reducing pain and stiffness in the joints.
Not only did we notice improvement in the rats' discomfort, but there were also positive changes seen in their joint health when examined under a microscope. We observed a decrease in markers of inflammation, suggesting that the dual treatment could provide a more effective path for managing knee pain in osteoarthritis patients.
Overall, this research highlights the potential benefits of combining curcumin with physical activity like swimming for easing knee pain due to OA.
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Turmeric combined benefits knee painA Retrospective Observational Study Evaluating the Synergistic Effect of a Novel Combination of Alfapin + Native Type 2 Collagen + Mobilee (Hyaluronic Acid) + CurQlife (Curcumin) Nutraceuticals in the Symptomatic Improvement of Knee Osteoarthritis.
Tumric's effect not isolated
In our analysis, we investigated how a blend of several natural ingredients, including turmeric (CurQlife, curcumin), might alleviate knee pain in individuals suffering from osteoarthritis. Our study focused on the effects of this combination of nutraceuticals, known as Clagen™, which also includes native type 2 collagen, hyaluronic acid, and other supportive components.
We enrolled 100 patients with knee osteoarthritis and monitored their progress over two months. At the end of this period, we noted a significant reduction in pain levels, as evidenced by improved Visual Analog Scale (VAS) scores. Additionally, there were noticeable enhancements in the range of motion and overall quality of life for the participants.
While turmeric was part of the combination, we can't isolate its specific effects from those of the other ingredients. Nonetheless, this study suggests that combining these natural substances may offer a beneficial strategy for managing knee pain, potentially reducing the need for traditional pain medications like NSAIDs in the long run. However, further long-term studies are needed to confirm these findings.
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User Reviews
Taking this drug with RSP Nutrition's Joint Support has significantly alleviated my knee pain without side effects. I'm very satisfied with the results.
Long-term use of curcumin has effectively relieved my knee pain and inflammation post-surgery.
Natural anti-inflammatory
Curcumin is a powerful natural anti-inflammatory that has helped me manage knee pain. Its effects on various inflammatory conditions, including arthritis and more, are impressive. A dosage of 1-1.5 grams is typically effective for pain relief.
I've been on curcumin for six months, and it has remarkably alleviated my knee pain. Initially, I struggled to walk, but after three months, my knee pain lessened significantly. I now take 2g daily, and I've reduced my other medications. Curcumin has made a considerable difference in my life.
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Jarrow’s curcumin has been excellent for managing my knee pain associated with rheumatoid arthritis. I highly recommend it.